Type 1 Medications
Most people with type 1 diabetes do not take oral antidiabetic medications, and the FDA has not approved any currently available diabetes medications for use in type 1 diabetes. However, some clinical studies have indicated that the type 2 diabetes drug metformin may be an effective adjunct, or complementary, therapy in some patients with type 1 diabetes who have also developed insulin resistance. The use of metformin for the treatment of type 1 is considered "off label." It has not been approved for use in people with type 1 diabetes.
Gomez R, Mokhashi MH, Rao J, Vargas A, Compton T, McCarter R, Chalew SA. "Metformin adjunctive therapy with insulin improves glycemic control in patients with type 1 diabetes mellitus: a pilot study." J Pediatr Endocrinol Metab. 2002 Sep-Oct;15(8):1147-51.
Reviewed by Francine Kaufman, MD. 4/08
Many people say that depression is a side effect or complication of diabetes. Without discounting the association of the psychological condition with the physical one, I'm not convinced that our high and/or unstable glucose levels are directly responsible for that change in our mental state. My belief is that the unrelenting need for self-care, for following the sort of care schedules that can drive licensed, professional caregivers crazy, is what overwhelms us...