Type 1 Medications
Most people with type 1 diabetes do not take oral antidiabetic medications, and the FDA has not approved any currently available diabetes medications for use in type 1 diabetes. However, some clinical studies have indicated that the type 2 diabetes drug metformin may be an effective adjunct, or complementary, therapy in some patients with type 1 diabetes who have also developed insulin resistance. The use of metformin for the treatment of type 1 is considered "off label." It has not been approved for use in people with type 1 diabetes.
Gomez R, Mokhashi MH, Rao J, Vargas A, Compton T, McCarter R, Chalew SA. "Metformin adjunctive therapy with insulin improves glycemic control in patients with type 1 diabetes mellitus: a pilot study." J Pediatr Endocrinol Metab. 2002 Sep-Oct;15(8):1147-51.
Reviewed by Francine Kaufman, MD. 4/08
Well maybe not so much a furor as a controversy. The question, bluntly put, is whether or not a single HbA1c reading should be sufficient and adequate to diagnose diabetes — and whether the conditions under which the test was conducted should have any bearing on the diagnostic or non-diagnostic value of the test. The lede from