Type 1 Medications
Most people with type 1 diabetes do not take oral antidiabetic medications, and the FDA has not approved any currently available diabetes medications for use in type 1 diabetes. However, some clinical studies have indicated that the type 2 diabetes drug metformin may be an effective adjunct, or complementary, therapy in some patients with type 1 diabetes who have also developed insulin resistance. The use of metformin for the treatment of type 1 is considered "off label." It has not been approved for use in people with type 1 diabetes.
Gomez R, Mokhashi MH, Rao J, Vargas A, Compton T, McCarter R, Chalew SA. "Metformin adjunctive therapy with insulin improves glycemic control in patients with type 1 diabetes mellitus: a pilot study." J Pediatr Endocrinol Metab. 2002 Sep-Oct;15(8):1147-51.
Reviewed by Francine Kaufman, MD. 4/08
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This past weekend was a whole lot of diabetes weird. I've finally gotten into a good rhythm with my Lantus rate - settling in with a 70-30 nighttime-morning split of the total dose. My bolus dosing seems to be pretty much on the money too. I'm avoiding huge swings... Though lows are creeping up more often, I think because summer traditionally is a lower basal rate time, owing to warmer weather, increased activity and sweat, as we get closer to the warmer days I just need less insulin in the...