What is LADA?
Type 1, Type 2 Misdiagnosis More Common Than You Think
Since my first pregnancy in 2000, I've had a lot of diabetes diagnoses thrown my way: gestational diabetes, prediabetes, insulin resistance, and one doctor told me I even had type 2 diabetes. But I was young, thin, in good shape, and no one in my immediate family had diabetes, so a type 2 diabetes diagnosis made no sense. Yet, no one thought to test me for type 1 diabetes, an autoimmune disorder, because I had none of the classic type 1 symptoms, like extreme thirst, weight loss, frequent urination, or diabetic ketoacidosis (DKA),
Eight years later, while pregnant with my third son, it became clear that something more than gestational diabetes or prediabetes was at play. I was exhausted all of the time, and an oral glucose tolerance test performed very early in the pregnancy showed blood glucose numbers over 250."I want to be tested for type 1 diabetes," I told my doctor. My doctor agreed and ordered a test for the antibody GAD, a marker of type 1 diabetes.
I went to the doctor's office to receive the results of my blood test. I had indeed tested positive for the GAD antibody. "You have type 1 diabetes," he said. "But it's probably LADA."
"LADA?" I said. I was vaguely aware of the term, but I had no idea what it meant. It turns out, I'm not alone. While almost everyone has heard of diabetes, next to no one (including most people with diabetes) knows what LADA is.
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Well maybe not so much a furor as a controversy. The question, bluntly put, is whether or not a single HbA1c reading should be sufficient and adequate to diagnose diabetes — and whether the conditions under which the test was conducted should have any bearing on the diagnostic or non-diagnostic value of the test. The lede from