FarxigaTM (dapagliflozin)

What is FarxigaTM?

FarxigaTM is the second drug in its class to be approved by the Food and Drug Administration. It is a type of SGLT-2 inhibitor that slows the glucose recovery process by the kidneys, thereby moving more glucose from the body into the urine. The extra glucose that passes into the urine is then eliminated from the body through urination thereby lowering glucose levels. This drug is to be used along with diet and exercise to help lower blood sugar for people with type 2 diabetes.

Who can take FarxigaTM?

Selected people over 18 years of age with type 2 diabetes.

Who should not take FarxigaTM?

People with type 1 diabetes or diabetic ketoacidosis and people with severe kidney problems or who are on dialysis should not take FarxigaTM and it should not be used if you have active bladder cancer. Your healthcare provider should do blood tests to check your kidney function before and during treatment with FarxigaTM.

What dosage can I take and how should I take it?

The initial dose is 5 mg, taken once daily by mouth in the morning with or without food. The dose may be increased to 10 mg daily upon the advice of your healthcare professional.

How often and when should I take FarxigaTM?

FarxigaTM should be taken once every day as prescribed by a medical professional. It can be taken with or without food. Your doctor will tell you exactly how much to take and when to take it.

What are possible side effects?

• The most common side effects that were reported in 5% (for every 100 people taking the medicine 5 of them had the side effect) were female yeast infections, nasopharyngitis (think cold and sore throat symptoms), and urinary tract infections. Other possible side effects include dehydration, penile yeast infections in men, changes in frequency of urination, hyperkalemia (too much potassium in the system), impairment of kidney function, low blood pressure, and increases in LDL cholesterol.

• Increased loss of water and sodium from the medication can cause dehydration. If you feel dizzy, faint, lightheaded, or weak, see your medical professional. Risk of dehydration may be further increased if you have low blood pressure, take medicines to lower your blood pressure, are on a low sodium diet, have kidney issues, or are 65 years of age or older.

• There are risks involved with urination of increased levels of glucose. Urinary tract infections can result from urine with high sugar concentration. Women who take this drug may get vaginal yeast infections and men may get a yeast infection of the skin around the penis. Talk to your doctor about what to do if you have symptoms of a yeast infection. Your doctor may suggest an over-the-counter antifungal medicine. Talk to your doctor right away if you use an over-the-counter antifungal medication and your symptoms do not go away. Taking this drug with some of the other diabetes medications can increase your risk of low blood sugar (hypoglycemia). If you experience symptoms including, headache, drowsiness, weakness, dizziness, confusion, irritability, hunger, rapid heartbeat, sweating, you may be experiencing low blood sugar.

Are other diabetes medications used with it?

FarxigaTM can be used in combination with other medicines. You are encouraged to consult with your doctor or pharmacist to learn about the interactions between FarxigaTM and the medications you are taking.

What should I tell my doctor before taking FarxigaTM?

Tell your doctor about any other medications you are on, as well as general allergies and allergies you have to the ingredients in FarxigaTM. Also, tell your doctor if you have diabetic ketoacidosis or a history of bladder cancer.

What else should I know before taking FarxigaTM?

Please see the accompanying FDA approved medication guide for more information about warnings and side effects.

 

Reviewed by Jimmy Bennet 05/2014

Get the Farxiga Medication Guide

Last Modified Date: June 09, 2014

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