PrintOnglyza
Brand Name (Generic Name)
Onglyza (saxagliptin)
What is Onglyza?
Onglyza is an oral prescription medicine used along with diet and exercise to control high blood sugar in adults with type 2 diabetes. Onglyza works by enhancing the body's natural ability to control high blood sugar; it lowers blood sugar by helping the body increase the level of insulin after meals. Onglyza is unlikely to cause your blood sugar to be lowered to a dangerous level (hypoglycemia) because it does not cause insulin to be secreted when blood sugar is normal or low. It can be used alone or together with one of several common oral diabetes medicines, such as metformin, a thiazolidinedione (TZD), or a sulfonylurea.
Who can take Onglyza?
Type 2 diabetes patients can use this prescription medicine.
Who can not take Onglyza?
Onglyza should not be used to treat people with type 1 diabetes or to treat diabetic ketoacidosis (dangerously high levels of certain acids, known as ketones, in the blood or urine).
It is not for patients who are taking insulin, as Onglyza has not been studied with insulin.
Talk to your doctor if you are pregnant or plan to become pregnant. It is not known if Onglyza will harm your unborn baby. Additionally, talk to your doctor if you are breat-feeding or plan to breast-feed. Onglyza may be passed in your milk to your baby.
When Onglyza is used with certain other diabetes medicines to treat high blood sugar, such as a sulfonylurea, low blood sugar (hypoglycemia) may occur. Symptoms of low blood sugar include shaking, hunger, sweating, headache, rapid heartbeat, change in mood, and change in vision. Follow your healthcare provider's instructions for treating low blood sugar.
If you have allergic (hypersensitivity) reactions, such as rash, hives, and swelling of the face, lips, and throat, stop taking Onglyza and call your healthcare provider right away.
When Onglyza is used with a thiazolidinedione (TZD), such as pioglitazone or rosiglitazone, to treat high blood sugar, peripheral edema (fluid retention) may become worse. If you have symptoms of peripheral edema, such as swelling of hands, feet, or ankles, call your healthcare provider.
What dosage can I take and how should I take it?
Take Onglyza by mouth one time each day exactly as directed by your doctor.Onglyza can be taken with or without food. During periods of stress on the body, such as fever, trauma, infection, or surgery, contact your doctor right away as your medication needs may change. Your doctor should test your blood before starting Onglyza and from time to time to measure how well your kidneys work. You may need a lower dose of Onglyza if your kidneys are not working well.
What are the side effects?
Common side effects of Onglyza include upper respiratory tract infection, urinary tract infection, and headache. These are not all of the possible side effects of Onglyza. Tell your doctor if you have any side effects that bother you or that do not go away. For more information, ask your doctor.
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