Combination Oral Medicines

Brand Name (Generic Name)

Actoplus Met (pioglitazone metformin)
Warning: thiazolidinediones, including pioglitazone, which is a component of Actoplus Met, can cause or worsen congestive heart failure in some patients. For more information on side effects, refer to the pioglitazone and metformin sections.

Avandamet (rosiglitazone maleate metformin hydrochloride)
Warning: thiazolidinediones, including rosiglitazone, which is a component of Avandamet, can cause or worsen congestive heart failure in some patients. Due to the side effects, Avandamet is now only available to patients who enroll in a special program. Talk to your doctor to get more information on the program. For more information on side effects, refer to the rosiglitazone and metformin sections.

Avandaryl (rosiglitazone glimepiride)

Duetact (pioglitazone glimepiride)

Glucovance (glyburide metformin hydrochloride)
For more information on side effects, refer to the glyburide and metformin sections.

Janumet (sitagliptin/metformin HCl)
For more information on side effects, see DPP-IV Inhibitors and biguanides.

Janumet XR (sitagliptin (Januvia) and metformin hydrochloride (HCl) extended-release) is a once-daily oral medication. For more information on side effects, see DPP-IV Inhibitors and biguanides.

Jentadueto (linagliptin/metformin hydrochloride) is a twice-daily oral medication.
For more information on side effects, see DPP-IV Inhibitors and biguanides.

Juvisync (sitagliptin and simvastatin)
For more information on side effects, see DPP-IV Inhibitors and Simvastatin.

Kombiglyze XR (saxagliptin/metformin)
Once-a-day metformin extended-release (XR) plus saxagliptin, a dipeptidyl peptidase-4 (DPP-4) inhibitor combination tablet. For more information, see DPP-IV Inhibitors and biguanides

Metaglip (glipizide metformin)

PrandiMet (repaglinide metformin HCl tablets)
A meglitinides and biguanides combination drug approved for use as an adjunct to diet and exercise in type 2 diabetes patients when response to repaglinide or metformin monotherapy is inadequate.

SOURCE:

Drugs.com. FDA Approves Jentadueto,(Accessed 2/6/12.)

Merk.com. Medication Guide for JANUMET® XR,  (Accessed 2/7/12.)

National Diabetes Information Clearinghouse. What I Need to Know About Diabetes Medicines. (Accessed 8/8/11.)

U.S. Food and Drug Administration. FDA Approves Combination Therapy Juvisync. (Accessed 10/7/11.)

Reviewed by Francine Kaufman, MD.

Last Modified Date: February 14, 2012


All content on dLife.com is created and reviewed in compliance with our editorial policy.
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