Januvia

Brand Name (Generic Name)

Januvia (sitagliptin phosphate)

These two hormones are responsible for increasing beta-cell insulin production and decreasing glucagons production in response to blood glucose levels, (i.e when blood glucose levels are high, insulin production is boosted and glucose production by the liver drops off). They amplify the response and reaction of a “normal” pancreas to high blood sugar levels. This mechanism does not work when your blood sugar is low so hypoglycemia is unlikely.

Sitagliptin phosphate has shown weight loss benefits in clinical trials. It also appears to preserve beta cell function.

How often should I take sitagliptin phosphate?

Once a day, as your doctor may suggest. Your doctor may also prescribe this medication in conjunction with metformin, Actos, or Avandia.

When should I take sitagliptin phosphate?

Sitagliptin phosphate can be taken with or without food. You doctor should tell you what will work best for you.

What are possible side effects?

  • Upper respiratory infection
  • Stuffy or runny nose and sore throat
  • Headache
  • Stomach discomfort
  • Diarrhea

SOURCE:

National Diabetes Information Clearinghouse. What I Need to Know About Diabetes Medicines. (Accessed 8/8/11.)

Reviewed by Francine Kaufman, MD.

Last Modified Date: August 11, 2011


All content on dLife.com is created and reviewed in compliance with our editorial policy.
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