Brand Name (Generic Name)

Cycloset (Bromocriptine)

Bromocriptine is the first-of-its-kind drug that increases dopamine in the brain in order to improve blood sugar control in people with type 2 diabetes. It has a rather weak blood sugar-lowering capability. Although the mechansim of action is not clear, it may centrally reverse many of the metabolic changes that are associated with insulin resistance and obesity.

Who can take Cycloset?

Selected patients with type 2 diabetes.

Who should not take Cycloset?

People with type 1 diabetes, ketoacidosis, or sensitvity to ingredients.

How is Cycloset taken?

Cycloset is taken once a day. The dose varies as tolerated up to 4.8 mg daily. It is taken within two hours of waking up and with food.

What are possible side effects?

Low blood pressure (hypotension), fainting, gastrointestinal symptoms, headache, dizziness, and weakness. Use may exacerbate psychotic disorders or reduce the effectiveness of drugs that treat psychosis.

Are other diabetes medicines used with Cycloset?

Should be used in combination with diet and exercise. Limited efficacy data in combination with thiazolidinediones. Efficacy has not been confirmed in combination with insulin.

Reviewed by James A. Bennett 05/13

Last Modified Date: May 28, 2013

All content on is created and reviewed in compliance with our editorial policy.

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by Carey Potash
Let me count the ways. Actually I can’t count the ways; there are too many. But let me begin with nasty carbohydrates and how they torture me. I’m considering making “How Do I Hate Thee?” a series of blog posts, exploring the many different things I despise about diabetes. There is so much to hate about diabetes, but this one I place high on my list. Last Wednesday, a friend offered me and...