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The Question
Wed Jun 17 11:48:27 UTC 2009

severe generalized pittingedema(5-8Kg)in 48 hrs after insulin.Have to omitt insulin to resolve.HbA1C 10. Normal kidney function. Why and how to avoid?
Asked By: hisham  
Category: Insulin

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Expert Answers (1)
2010-03-02 23:27:41.0

The use of Insulin along with TZDs such as Avandia or Actos can contribute to severe edema. It is also possible to experience insulin induced edema due to sudden drops in blood glucose following periods of prolonged insulin deficiency. In such case the edema is a temporary response to changes in fluid balance, which can be minimized through gradual decrease in blood glucose levels and appropriate medically supervised restoration of fluid and electrolyte balance.
Answered By: Claire Blum
Accreditations: MS Ed, RN, CDE, CPT
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