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The Question
02/12/10 03:57 PM

"In switching from NPH to Lantis is there anything I should be aware of? Does Lantis have any unique side effects? Is it harder on the kidneys?"
Asked By: sagecanoe  
Category: Kidney Disease

Background Info Hide
I have just been diagnosed with the early stages of Kidney disease and the doctor thinks that Lantis will give me better glucose control and so prevent further damage. Since I have low blood pressure, ACE inhibitors are not an option.

Expert Answers (1)

02/19/10 12:05 AM

Thanks for writing dLife. Your question is very good as there are distinct differences between NPH insulin and Lantus insulin. The main difference is that while NPH insulin starts to work about 2 hours after injection and has a peak of action starting about 4 hours until about 12 hours and then "tails" off, (depending on dosage and other variables), Lantus does not peak and is usually taken only once per day since it's effectiveness lasts for most of 24 hours. Neither insulin is harder on the kidneys- what is hard on the kidneys is poor blood sugar control as well as poor blood pressure control. So it is likely that your doctor may think that your blood glucose level may be better controlled with Lantus based upon your glucose testing and lab results. It is typically recommended that with any change in therapy, you test your blood glucose levels more frequently to see how your body adapts to the change, and share these results with your doctor. Best of luck to you!
Answered By: Janice Baker
Accreditations: B.Sc., MBA, RD, CDE, CNSC
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