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The Question
11/20/09 07:42 PM

"I have Type 2 and had been taking glucophage XR. Glucophage has been discontinued for 1+ year. Why is my lactic acid is still running a little high ?"
Asked By: dljolly  
Category: Type 2

Background Info Hide
I was told that discontinuing the glucophage would probably make the lactic acid come down; however, it came down to nearly normal and then has started to climb again. I am taking Lantus insulin.

Expert Answers (1)

12/18/09 07:05 PM

Hello DlJolly: Thank you for bringing your question to dLife. The discontinuance of glucophage suggests you are predisposed to lactic acidosis, a potential fatal metabolic condition. Glucophage is discontinued if you have potential renal impairment, (what is the status of the renal indicators?, creatinine levels >1.5 mg/dl in men and >1.4 mg/dl in women suggest some involvement), the use of glucophage is also contraindicated in the presence of moderate to severe heart failure, again, due to the risk of lactic acidosis and worsening of heart failure or renal conditions. The accumulation of lactic acid indicates that the balance between lactate production and utilization has been disturbed. Lactic acid, normally present in the blood and muscle tissue are a product of normal metabolic functions and eliminated via the urine. Careful monitoring of your health status is important.

Causes for the slight elevation in the lactic acid levels could be due to :

  • deficiency of adequate oxygen utilization, or some impaired circulations to tissues and functions, which may also be complicated by the pre-existing diagnosis of diabetes
  • kidney malfunctions
  • or simple dehydration, inadequate fluid intake.
    Clarification is best obtained from your personal physician, keep a list of questions, take into the next appointment.

    Action you can take, maintain adequate hydration, (observe any other medical fluid restrictions if any), adequate fluid intake is described as 6-8- 8ounces of plain water daily. Maintain good circulation, (as to assure proper oxygen perfusion of all tissues), activity to 150 minutes/week, per tolerance,as well as medical clearance: you could try the "Chair Dancing" video we seniors do at our local library, or check out the websiteClick here to read it. ADA's ABC's: A1C<7%,BP<130/80 mm Hg, Total cholesterol<200,LDl<100 mg/dl. Be your best, regards Sue

    • Answered By: Susan Throop
    Accreditations: RD, CDE, MA
    Sources Show

    Community Answers (0)

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    *** All information contained on dLife.com is intended for informational and educational purposes only. Our Expert Q&A is not intended to be a replacement or substitute for consultation with a qualified medical professional or for professional medical advice related to diabetes or another medical condition. Please contact your physician or medical professional with any questions and concerns about your medical condition.

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