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The Question
05/26/09 11:01 PM

"i have brown patches all over skin from i guess being really ir what can i do to get rid of it .or is there some kind medicine i can use? its nasty "
Asked By: lisa81  

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looking and people make fun of. also its getting alot worse than before. i am taking 65 lantus moring,30mg actos, morning and 150 lantus night and 30 units each meal of humlin u-500 r insulin . is there a medicine for being ir or to help it besides metformin cause can't take that .or avinida.

Expert Answers (2)

05/29/09 06:51 AM

Hello Lisa81; PS-there are some prescriptive medications for the brown spots, you'll need to speak to your PCP, it is a retinoic acid (tretinoin, Retin-AAE)product, this may be used on the lesions. Be your best in '09, keep up the good work. Regards again, Sue
Answered By: Susan Throop
Accreditations: RD, CDE, MA
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05/28/09 04:26 PM

Hello Lisa 81; Insulin resistance, I hear your frustration. Remedy for brown spots, also know as 'acanthosis nigricans.' (I'm guessing, the conditions are described in the literature). Described as occurring with IR, but, treatment is the classic!!! Causes of insulin resistance include genetic cellular receptor and post receptor defects, genetic ethnicity, high levels of free fatty acids, hormonal antagonists, or acquired factors (obesity, inactivity or smoking). Ok what can we change here??? The one main physical sign of insulin resistance is 'acanthosis nigricans', a tan-like darkening of the skin usually located at the back of the neck, elbows, knees or knuckles. Treatment would begin by observing all the 'good' management' recommendations. A-A1C<7, Lipids, LDL<100, HDL>70, BP<130/90, WT-BMI<25, activitiy >150minutes/week. Tall order, seek out support, I would encourage contacting your local hospital to get signed up for their certified diabetes educaiton program, CDE-RN, CDE-RD, are a couple of people with expertise to help with self-management of this insidious disease. The proof of effectiveness of your hypo-glycemic meds; Are they achieving your target goals??? Several other medications are available, however, a personal conversation with your Endocrinologist is indicated here. IR, No cure but, some successful treatment options available. Good luck and thanks for asking dLife. Call on us as needed. Regards Sue for You1
Answered By: Susan Throop
Accreditations: RD, CDE, MA
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Community Answers (1)

05/30/09 03:23 PM

I actually learned something I did not know today about the brown spots. I do have IR but no spots and I know I have struggled over the last 24 yrs no matter what I do my diabetes is very genetic. Good luck I did find reducing refined carbs did help me out.
Answered By: furball64801
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*** All information contained on dLife.com is intended for informational and educational purposes only. Our Expert Q&A is not intended to be a replacement or substitute for consultation with a qualified medical professional or for professional medical advice related to diabetes or another medical condition. Please contact your physician or medical professional with any questions and concerns about your medical condition.

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