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Epigenetic Changes Could Explain Type 2 Diabetes

Posted by dlife on Mon, Mar 10, 14, 09:05 AM 0 Comment

March 7, 2014 (Eureka Alert) — People with type 2 diabetes have epigenetic changes on their DNA that healthy individuals do not have. This has been shown in a major study by researchers at Lund University. The researchers also found epigenetic changes in a large number of genes that contribute to reduced insulin production.

"This shows that the risk of developing type 2 diabetes is not only genetic, but also epigenetic", said Charlotte Ling, who led the study.

Epigenetic change

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Exercise Training Modestly Improved Insulin Levels of Children, Adolescents

Posted by dlife on Thu, Dec 26, 13, 01:27 PM 0 Comment

December 26, 2013 (Healio) - Exercise training appears to provide some benefit to fasting insulin and insulin resistance in children and adolescents, according to a recent meta-analysis published in the journal Pediatrics.

"The prevalence of obesity and diabetes is increasing among children, adolescents and adults," the study researchers wrote. "Although estimat

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Type 2 Diabetes in Women Less Than 45 Triples Risk of Early Menopause

Posted by dlife on Mon, Dec 23, 13, 02:07 PM 0 Comment

December 23, 2013 (News-Medical) - Type 2 diabetes - the most common type of diabetes - triples the risk of an early menopause in women younger than 45 years of age, according to new research published in the peer-reviewed journal Climacteric.

Diabetes is a huge and increasing international problem. The International Diabetes Federation estimates that 366m people had diabetes in 2011 - more than the entire po

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A Wrong Molecular Turn Leads Down the Path to Type 2 Diabetes

Posted by dlife on Fri, Dec 20, 13, 03:41 PM 0 Comment

December 20, 2013 (ANL) - Computing resources at the U.S. Department of Energy's (DOE) Argonne National Laboratory have helped researchers better grasp how proteins misfold to create the tissue-damaging structures that lead to type 2 diabetes. The structures, called amyloid fibrils, are also implicated in neurodegenerative conditions such as Alzheimer's and Parkinson's, and in prion diseases like Creutzfeldt-Jacob and mad cow disease.

The results pinpoint a critical inter

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Escape from Poverty Helps Explain Diabetes Epidemic in the American South

Posted by dlife on Tue, Aug 06, 13, 10:50 AM 0 Comment

August 5, 2013 (Newswise) — The strikingly high prevalence of Type 2 diabetes in the American South can be partially traced to rapid economic growth between 1950 and 1980, new research suggests.

The study tests the "thrifty phenotype" hypothesis, which suggests that if economic conditions present during fetal development improve dramatically during a person's childhood, the prospects of poor health in adulthood increase.

According to the hypothesis, children whose parents endured being poor were unprepared biolog

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