Diabetes News

Archive - 09 - 2014

Exercise May Not Lower Diabetes Risk Equally in All Patients

Posted by dlife on Tue, Sep 30, 14, 11:24 AM 0 Comment

September 30, 2014 (DailyRx) - Exercise has many beneficial effects on health. One of those benefits is as a reduced risk for type 2 diabetes. But exercise may not reduce that risk by the same amount for everyone. A research team at the University of Arizona in Tucson recently studied how exercise affected type 2 diabetes risk in different groups. They found that, although exercise lowered risk in almost all patients, it didn't lower it equally across the board. People with a high genetic risk for diabetes saw fewer benefits from exercise ? and this was more pronounced in women than men. Type 2 diabetes is marked by resistance to insulin, a hormone that regulates blood sugar. Researchers have long believed that exercise could reduce patients' risk of this chronic disease. Drawing data from a past study, Yann Klimentidis, PhD, and colleagues studied how exercise affected patients' risk for type 2 diabetes. Of the patients in the past study, 821 had type 2 diabetes. All were white men and women between 45 and 64 years old. The study authors assigned each patient genetic risk scores (GRS). These measured 65 genetic variants associated with a raised risk type 2 diabetes ? known as single nucleotide polymorphisms (SNPs). People with these SNPs face a raised risk of type 2 diabetes. One GRS looked at all 65 SNPs, while others looked at specific risks for diabetes, such as insulin resistance, fasting insulin and glucose levels. Those who had high GRSs saw the fewest protective benefits from exercise, the authors found. They also noted that, overall, women did not gain as many benefits from exercise as men. The study authors concluded that exercise did protect against type 2 diabetes overall, but this effect was weakest in women and those at high genetic risk. Genetic risk appeared to trump protective measures. The study authors noted that the group of patients they studied was not diverse in age or race and the patients self-reported much of the data. The authors called for more research. This study was published online Sept. 29 in Diabetologia. The National Institutes of Health funded the study. The authors disclosed no conflicts of interest.

Work Type, Duration May Influence Diabetes Risk

Posted by dlife on Mon, Sep 29, 14, 09:54 AM 0 Comment

September 26, 2014 (HealthDay) - Working long hours may increase your risk for diabetes, a new study suggests. But the finding seems to depend on your job. Researchers examined data from prior studies involving more than 222,000 men and women in the United States, Europe, Japan and Australia who were followed for an average of 7.6 years. The initial analysis revealed no difference in the risk of type 2 diabetes among people who worked more than 55 hours a week and those who worked 35 to 40 hours a week. However, further analyses showed that people who worked more than 55 hours a week at manual labor or other types of "low socioeconomic status jobs" were 30 percent more likely to develop diabetes than those who worked 35 to 40 hours a week. This increased risk remained even after the researchers accounted for diabetes risk factors such as smoking, physical activity levels, age, sex and obesity, and after the researchers excluded shift work, which increases the risk of obesity and diabetes. Although the study, published Sept. 24 in The Lancet Diabetes & Endocrinology, found an association between long work weeks and diabetes, it didn't establish a cause-and-effect relationship. Further research is needed to learn more about the seeming link between working long hours and increased diabetes risk, the study authors said. Possible explanations include the fact that people who work long hours have little time for healthy behaviors such as exercise, relaxation and adequate sleep. "Although working long hours is unlikely to increase diabetes risk in everyone, health professionals should be aware that it is associated with a significantly increased risk in people doing low socioeconomic status jobs," Mika Kivimaki, professor of epidemiology at University College London in England, said in a journal news release. The authors of an accompanying journal commentary said the findings may have implications for diabetes-prevention programs. The study findings remained strong "even after controlling for obesity and physical activity, which are often the focus of diabetes risk prevention, suggesting that work factors affecting health behaviors and stress may need to be addressed as part of diabetes prevention," Dr. Orfeu Buxton, of Pennsylvania State University, and Dr. Cassandra Okechukwu, from Harvard School of Public Health, wrote.

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