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Archive - 09 - 2013
Type 1 diabetes may increase risk of multiple sclerosis and environmental factors may play a role
September 28, 2013 (dailyRx News) For young people, type 1 diabetes may raise the likelihood of having multiple sclerosis. Scientists now suspect that certain environmental factors may play a role.
Type 1 diabetes and multiple sclerosis (MS) are both autoimmune diseases, meaning a person's immune system causes damage to their own body.
Type 1 diabetes (sometimes called juvenile diabetes because it is usually diagnosed in childhood) is an autoimmune attack against the beta cells in the pancreas while, with multiple sclerosis, the immune system attacks the brain and spinal cord.
Recent research backed up previous studies which found that children and adolescents with diabetes face greater odds of getting MS. Investigators discovered that environmental factors, including when a person is born, may heighten this risk.
Susanne Bechtold, MD, in the Department of Pediatrics, Medical University Munich, Germany, and a team of researchers analyzed data on 56,653 children and adolescents with type 1 diabetes under the age of 21 from Germany and Austria.
The authors discovered 19 of these patients had MS.
Researchers compared MS prevalence rates from the Mid-European and German MS pediatric and adult registers with their data. They calculated an MS prevalence of 7 to 10 patients per 100,000 with type 1 diabetes, compared with 3 to 5 cases per 100,000 in a non-diabetes population.
The risk of the diabetes patients having MS was three to almost five times greater.
The investigators also cited three possible influencing factors that could be adding to the risk of developing MS—immigration status, thyroid antibodies (only in males) and month of birth.
There was a higher MS risk in patients with an immigrant background. The authors wrote "...we assume that variations in their genetic, environmental or cultural background caused this significantly increased risk to simultaneously develop type 1 diabetes and MS."
Male patients with thyroid specific antibodies also had a higher chance of developing MS. Thyroid antibodies are an immune response of the body, which is considered to be abnormal.
Also, researchers noted that among the diabetes-MS patients, dates of birth peaked in June and August.
Dr. Bechtold told dailyRx News, "We think that environmental factors might influence the immunological system, like by vitamin D level during early pregnancy. The theory regarding month of birth is that vitamin D has immune-modulating capacities."
This study found that two-thirds of patients with type 1 diabetes and MS had a birth month consistent with the fetus having experienced lower levels of ultraviolet exposure during early pregnancy. Exposure to sunlight can be a source of vitamin D.
"Overall this is speculation and I am not aware on any study investigating the influence of different environmental factors in detail on the fetus," said Dr. Bechtold.
The authors qualified their results, writing that the low number of MS patients did not reach statistical significance.
"In the next step, we are going to contact each of the 19 patients to get more detailed information of history, family history and immunological data," Dr. Bechtold told dailyRx News. "Only with these hopefully more detailed knowledge we may give advice."
The study was published online in September in Diabetes Care ahead of print.
September 24, 2013 (Newswise) — A recent study in Nature Communications found that for mice following a diet containing 25 percent extra sugar—which is the mouse equivalent of a healthy human diet plus three cans of soda or other sweetened beverage daily—the females died at twice the normal rate and males were 25 percent less likely to hold territory and reproduce. The results were based a toxicity test developed at the University of Utah. The researchers concluded this is evidence that sugar consumed at concentrations currently considered safe has a dramatic adverse impact on mammal health, and demonstrates the adverse effects of sugar in the human diet. "The National Research Council recommends that people consume no more than 25 percent of their daily calories from ‘added sugar,'" say boomer generation health experts Dian Griesel, Ph.D., and Tom Griesel, authors of the books TurboCharged: Accelerate Your Fat Burning Metabolism, Get Lean Fast and Leave Diet and Exercise Rules in the Dust (April 2011, BSH) and The TurboCharged Mind (January 2012, BSH). "This recommendation doesn't include what is naturally in fruits, vegetables, grains and other non-processed food," adds Tom. "Up to 25 percent of Americans consume this ‘recommended' amount, and many consume even more. The 25 percent sugar-added diet for mice is the equivalent of a human drinking three cans of sweetened soda or other beverage daily, along with an otherwise healthy, no-sugar-added diet. Sugar consumption in America has increased 50 percent since 1970. During this period we have seen a dramatic increase in metabolic diseases such as diabetes, obesity, fatty liver and cardiovascular disease. There seems to be no safe dose of added sugar, so total avoidance is advised if you are interested in optimal health and longevity." About TurboCharged: TurboCharged is a groundbreaking 8-Step program that defies common weight-loss theories. It successfully delivers body-defining rapid fat loss, accelerates metabolism, and improves health and odds of longevity without gimmicks, supplements or special equipment. The TurboCharged Mind is an excellent companion book to the author's acclaimed rapid fat loss book, TurboCharged, or perfect as a standalone read. A series of supporting TurboCharged™ hypnosis downloads are available for sale via the book's website, which offers ideal guided meditations to support and direct self-hypnosis sessions for faster fat loss, greater health, reduced stress, and to quit smoking. For more information, log on to http://www.turbocharged.us.com.
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