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Marijuana May Be Effective for Neuropathic Pain

Posted by dlife on Wed, Jun 25, 08, 10:10 AM 8 Comments

June 25, 2008 (Newswise) - The growing body of evidence that marijuana (cannabis) may be effective as a pain reliever has been expanded with publication of a new study in The Journal of Pain reporting that patients with nerve pain showed reduced pain intensity from smoking marijuana.Researchers at University of California Davis examined whether marijuana produces analgesia for patients with neuropathic pain. Thirty-eight patients were examined. They were given either high-dose (7%), low-dose (3.5%) or placebo cannabis.

The authors reported that identical levels of analgesia were produced at each cumulative dose level by both concentrations of the agent. As with opioids, cannabis does not rely on a relaxing or tranquilizing effect, but reduces the core component of nociception and the emotional aspect of the pain experience to an equal degree. There were undesirable consequences observed from cannabis smoking, such as feeing high or impaired, but they did not inhibit tolerability or cause anyone to withdraw from the study. In general, side effects and mood changes were inconsequential.

It was noted by the authors that since high and low dose cannabis produced equal analgesic efficacy, a case could be made for testing lower concentrations to determine if the analgesic profile can be maintained while reducing potential cognitive decline.

In addition, the authors said further research could probe whether adding the lowest effective dose of cannabis to another analgesic drug might lead to more effective neuropathic pain treatment for patients who otherwise are treatment-resistant.

Source: A Randomized, Placebo-Controlled, Crossover Trial of Cannibis Cigarettes in Neuropathic Pain; Barth Wilsey, Thomas Marcotte, Alexander Tsodikov, Jeanna Millman, Heather Bentley, Ben Gouaux and Scott Fishman, University of California Davis

Comments

I have to say a comment r

I have to say a comment related to Doug's comment a bove, I agree that couple arrested by the cops was probably really calm, many are when cought with dope on them but that is recreational smoking and I don't agree with recreational smoking because they were just as "drunk like" as the others and if cought driving should be arrested too no matter how calm they may be. They are out to be high and I hate to see the need for pot as a medicine getting confused with the use of it out on the street as a recreation. The few times I have done it for my pain, I did it in my home and relaxed as a medicine, I did not go out on the town with it on me. There has to be a separation between using it as a pain reliever, a few drags and partying with it. This is part of why it is so hard to leagalize it as a medicinal drug. I know when I was younger I did it as a recreational thing a few times because it was brought to a party and even my house a few times, (not that I asked for it to be brought there) and I never did feel it was right to do it even tho I did it. Now I do if it works to help a pain condition. I just hope when people apply to use it leagally they are doing it for pain and not to have a right to be hanging out on the street or driving a car. I also don't like to see it done in the work place because I have seen people in my old work place who did it and acted like they were the only important ones there, You should see the few I knew who were doing it while driving forklifts around other workers, Hot headed (not so calm like you saw on the cop show). A lot of near miss accidents and even one where a lady had her foot ran over and another where the driver saw a pallet of stuff coming down on him while in his forklift and he stuck his hand up through the bars thinking he could stop it from hurting him. Had he kept his hand in the cage he would have had no injury. Those people are smoking too much and that is what makes it a problem. As I said above, I have in my past smoked enough to get high and have smoked enough to relieve pain and the amount needed for pain is very different. I used a hole pot smoke over the course of over two days when my pain was really bad and it was effective enough to do the job without feeling high at all. Whats more, it was instant pain relief and works for what is called break through pain which many pain med prescribed people find is a real problem too. The sad part is the pain meds I am on need to be used twice daily or they will not work so I have to be on drugs constantly and yet the relief is minimal (only covers day to day continual pain at best and does not cover spikes) compared to what pot has done with so little and yet so fast and even covering the whole pain from the continual to the burning and the spikes that come and go on a bad day. I know if I could use it only when the pain is bad enough to need it with a mild pain reliever for the daily stuff I could probably cope better on a daily basis.

I have known for 30 years

I have known for 30 years that weed helps with pain relief. There are some secrets that just shouldn't be kept.

I have known or known of

I have known or known of so many people who suffered extreme pain due to neuropathy. I am an advocate for the medical use of marijuana for whatever medical conditions may benefit. To deny people the potential benefit of marijuana because of the possibility of abuse is to "throw the baby out with the bathwater". I hope someday that this country will develop a saner approach to the use of marijuana and other such substances that may have therapeutic benefits.

I would like the choice f

I would like the choice from man made pain relievers to natural pain relievers.I TRUELY BEIEVE MAN MADE PILLS ARE GOING TO AID IN MY PREMATURE DEATH I HAVE TO STOP THESE PILLS ON MY OWN OF SUFFER THE COST. I think pot definitaley helps one to forget out the pain for about 3 hours at around a quarter to a half a ciggerette. I ALSO THINK PEOPLE WHO CAN NOT STOP THINKING ABOUT A ILLNESS THAT HAS TAKEN OVER THERE LIFE POT WOULD MOST DEFINITELY GIVE THAT PERSON THE MUST NEEDED BREAK OF DWELLING ON ONES PROBLEM AND MAY INFACT HELP THEM TO DO MORE POSITIVE THINGS LIKE EXERSISE FOR EXAMPLE. I KNOW FOR ME SINCE IT IS ILLEGAL I DO NOT PERTICIPATE IN THE SMOKING OF POT HOWEVER THE STRENGTH OF TODAYS POT THE PATEINT WOULDN'T NEED AS MUCH AS ONE WOULD THINK ONE POT CIGGERETTE SHOULD LAST THE PATEINT ALL DAY RELEVE.IN CLOSEING I WOULD LIKE THE CHOICE I THINK OUR GOVERMENT WOULD MAKE A HUGE WINFALL OF TAXES THAT COULD GO TO SOMTHING GOOD LIKE OUR RODAS OR ANYTHING POSITIVE, AS WELL THE PEOPLE PUT IN JAIL FOR POT THINK OF THE HUGE SAVINGS WE WOULD GET IF WE PUT REAL CRIMINALS IN JAIL. ALSO I WOULD LIKE TO COMMENT ON A SHOW CALLED COPS I DON'T REALLY CARE FOR THAT SHOW HOWEVER THIS TIME I HAPPEN TO WATCH THE PROGRAM ANYWAY IT WAS ABOUT DRUNK DRIVERS ON ANY GIVEN FRIDAY NIGHT. I BELEIVE ABOUT TWENTY DRUNK DRIVERS WERE ARRESSTED THAT SHOW 90 PERCENT WERE RUDE OR ACTING STUPID OR SICK AND HALF WERE VIOLENT AND NEEDED RESTRIANTS. THEN THERE WAS A COUPLE WHO WERE ARRESSTED FOR POT AND I COULD NOT BELIEVE THE CONTRAST THE COUPLE WHO HAD THE POT WERE SO MELLOW AND POLITE AND QUITE IT WAS QUITE A EYE OPENER. I WISH EVERYONE COULD SEE THAT SHOW I SAW THAT NIGHT.

I have Neuropathic Pain f

I have Neuropathic Pain from diabetes, My Mom and my sister also, If cannabis was legal, I would consider it to help my Pain.

I am happy to hear that t

I am happy to hear that this study points toward testing of lower doses for effectiveness. As a newly "licensed" user under California law, I have been treating cannabis as I treat any prescribed medication, working with my provider to find the optimal dose, both for maximizing benefit and minimizing undesirable effects. I have been surprised by how small an amount of cannabis can be effective, compared to the amount commonly ingested in social, casual, or "self-medicating" use. I look forward to more research in this area.

i personaly would indulge

i personaly would indulge in smokeing marijuana for pain amoung other things like depression.it has in the past helped me to forget about the things that were depressing me, and helping me to get on with my life.unfortunatly,the work world does,nt care if you are depressed or in pain.neither does the law.so unless something happens in the future,we are bound by the laws of the land and must deal with what ails us in a differant way,or god forbid,risk a life in prison.

I was never a smoker of m

I was never a smoker of marijawana but had tried it at various times of my life never becoming addicted to it. I tried it recently when my boss told me I should for my neuropathy and the responce was fast. two small drags and I snuffed it out and waited, barely a minute and i could feel no pain and from the loss of the pain a relaxed feeling but I didn't feel high either. I still don't do it as a rule but have the very odd time when the pain is really bad. Instead I finally choose medicine and am trying the third with no real huge pain relief. Infact I had brain fog with some of the pain killers for the first few days/ weeks depending on the drug and still get it now and then when I wake up so what is everyone making such a fuss about marijuanna for? I have to say as a non smoker of the weed I will when it gets so bad that I need to if these other drugs don't do the job. I would like to see testing on other levels of these drugs,,, A comparison on the long term affects of the medical drug as compared to long term affects of weed. After that I will decide what is best for me and if weed is best and I am not allowed I will just do it like people who do it for fun,,,, out on the back steps somewhere.

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