Initial data show a positive trend in controlling diabetes, the chronic disease that affects 21 million
Americans and costs the U.S. more than $174 billion annually. The final DTCC report, due out in
2009, will include cost-savings data for DTCC employers.

The Diabetes Ten City Challenge (DTCC) is an employer-based diabetes self-management
program conducted by APhA Foundation with support from GlaxoSmithKline. Since it was
launched in October 2005, 31 employers in ten cities have joined forces with hundreds of
pharmacists to help more than 1,000 people manage their diabetes.

Through the DTCC, employers establish a voluntary health benefit for employees, dependents and
retirees with diabetes, and waive co-payments for diabetes medications and supplies if they work
with a pharmacist “coach” to manage their condition in collaboration with their doctors and diabetes
educators. The DTCC is modeled after other highly successful APhA programs that have proven
to improve overall health, reduce absenteeism, shorten hospital stays and reduce health care
costs.

“The results to date prove that this collaborative-practice model is effective for managing diabetes
and replicable in diverse locations and employers,” said William M. Ellis, CEO of the APhA
Foundation and co-author of a peer-reviewed article on the results published in the March/April
issue of the Journal of the American Pharmacists Association (JAPhA). “In years of experience
with this model we have seen that when you have positive clinical outcomes and increased patient
satisfaction in the early stages, the economic benefits follow.”

Key Findings

The report released today analyzed aggregate data on 914 DTCC participants who were in the
program at least three months as of September 30, 2007. It documented clinical improvements in
all the recognized standards for diabetes care, including:

• Decreases in laboratory measures (mean) for hemoglobin A1C (a laboratory test showing the
patient’s average blood sugar control over the previous two to three months), LDL cholesterol
and blood pressure over the initial year of the program
• Increases in the number of participants with current influenza vaccinations, foot examinations
and eye examinations
• 21% increase in the number of participants achieving the American Diabetes Association goal
of A1c level <7.0
• Increase from 43.8% to 57.7% in participants achieving nationally recognized National
Cholesterol Education Program goals for LDL cholesterol
• 15.7% increase in the number of people achieving recognized goals for systolic blood
pressure

Other Key Data

• The number of DTCC participants who felt their overall diabetes care was “very good to
excellent” increased from 39% to 87%
• More than 97% of participants reported being “very satisfied” or “satisfied” with diabetes care
provided by DTCC pharmacists
• The number of participants with self-management goals to control their diabetes also
increased significantly over the course of the program: the number of people with nutrition
goals increased from 22% to 66%; the number of people with weight goals increased from
23% to 64%; and the number of participants with exercise goals increased from 24% to 72%

“The data show significant improvement in all clinical and diabetes care indicators measured,” said
Toni Fera, PharmD, principal author of an article on the results appearing in the March/April issue
of the Journal of the American Pharmacists Association. “These results are consistent with data
from past projects where similar clinical improvements translated to annual savings to employers in
total direct medical costs for participants."

"Chronic diseases like diabetes are threatening the stability of our healthcare system," said
GlaxoSmithKline President of U.S. Pharmaceuticals, Chris Viehbacher. "By focusing on patients
and helping them to better understand and self-manage their condition, we can improve their
health and lower costs. GSK is proud to support the Diabetes Ten City Challenge because it is a
model that works and can be replicated.”

How the DTCC Model Works

The APhA Foundation contracts with employers, helps establish local pharmacist networks and
provides software and data analysis for the DTCC. Employers offer the voluntary employee benefit
and compensate pharmacists for the care provided. Participating pharmacists, who are specially
trained in diabetes care, educate participants on diabetes, diet and nutrition. These “pharmacist
coaches” meet with participants regularly to help them track key diabetes indicators and manage
their diabetes by eating right, exercising regularly, visiting their doctors and taking medications as
prescribed.

Physicians are informed of participants’ enrollment and are encouraged to share individual patient
care plans with the pharmacist, who reinforces those plans in personal meetings. Pharmacists
communicate with physicians after every visit and refer patients to other health care providers as
needed for additional care or education.

Expanding the DTCC Model for all Chronic Diseases

An additional 50 employers and 1,300 employees are using the DTCC model through the APhA
Foundation’s HealthMapRx™ to manage many chronic diseases, such as diabetes and
cardiovascular disease.

“The Diabetes Ten City Challenge provides an opportunity to transform health care delivery in
local communities and drive fundamental change in the U.S. health care system,” Ellis said. “Our
overall goal is to make this model as widely available as possible and encourage employers to
invest in helping their employees manage all chronic conditions. Our nation’s health care system
is broken – we need more programs that are an investment in wellness rather than an expense for
sickness.”

About the APhA Foundation (www.aphafoundation.org)

The American Pharmacists Association (APhA) Foundation, headquartered in Washington, D.C., is
a non-profit organization affiliated with the American Pharmacists Association, the national
professional society of pharmacists in the United States.

The APhA Foundation has expertise in designing programs that seek to create a new medication
use system in the U.S. where patients, pharmacists, physicians and other health care providers
collaborate to dramatically improve the cost and quality of consumer health outcomes through the
safe and effective use of medications.