Crestor Outcomes Study JUPITER Closes Early Due To Unequivocal Evidence Of Benefit
March 31, 2008
Digg This! | Send to Newsvine | Add to del.icio.usMarch 31, 2008 (Press Release) - AstraZeneca today announced it has decided to stop the CRESTOR JUPITER clinical study early based on a recommendation from an Independent Data Monitoring Board and the JUPITER Steering Committee, which met on March 29, 2008. The study will be stopped early because there is unequivocal evidence of a reduction in cardiovascular morbidity and mortality amongst patients who received CRESTOR when compared to placebo.
JUPITER (Justification for the Use of statins in Primary prevention: an Intervention Trial Evaluating Rosuvastatin) was designed to determine if treating patients with no evidence of pre-existing cardiovascular disease and low to normal LDL-C but elevated C-reactive protein (CRP) with CRESTOR 20mg once daily would reduce major cardiovascular events. CRP is a recognized marker of inflammation and is associated with an increased risk of atherosclerotic cardiovascular events.
The JUPITER study team has initiated activities to close this large multi-centre study. Over 15,000 trial participants will be scheduled by their investigator for final assessments at over 1,200 sites in 26 countries. Data from these visits will be collected and reviewed to allow a full and complete analysis and final results of the study will be published once the analysis is complete.
JUPITER is one study from the global research initiative known as the GALAXY programme, which has now recruited more than 64,000 patients from 55 countries worldwide, to investigate the impact of CRESTOR on cardiovascular risk reduction and patient outcomes.
Posted by dlife at March 31, 2008 03:22 PM
Comments
Is this saying that Crestor does not work.
I have had 2 stents put in in 2004 and have been on Crestor but in 2007 it was changed to VyTorin 10/20 because I thought I had pains in my muscles and bones but recently (the last 3 Months) went back on Crestor 10 Mg. I am very concerned about if it is working for me. I will have a Cholesteroal check the middle of April but will that really tell if my arteries are OK?
Posted by: Lois at April 3, 2008 11:52 PM