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May 22, 2015 (Medical Daily) - Anyone looking to lose weight knows they have to restrict the amount of calories they consume, but how much and when they restrict those calories can make all the difference. A recent study conducted at Ohio State University has revealed that skipping meals not only leads to abdominal weight gain, but it can also lead to the development of insulin resistance in the liver.
"This does support the notion that small meals throughou
May 21, 2015 (MedicalXPress) — Several recent studies have suggested that metformin, an established drug developed to treat patients with type II diabetes, may provide significant benefits, including increased survival, to patients being treated for advanced cancers. An analysis of combined results from these earlier studies found that metformin use was associated with a significant decrease in cancer risk, tumor burden and cancer mortality.
The University of Chicago M
May 21, 2015 (MedicalXPress) — Alternative splicing of obesity and type 2 diabetes related genes may contribute to the pathophysiology of obesity, according to research from the University of Eastern Finland. Obesity leads to changes in the splicing pattern of metabolically relevant genes such as TCF7L2 and INSR, resulting in impaired insulin action. However, weight loss, induced by either obesity surgery or a very low-calorie diet, reverses these changes. The findings, presented
Joslin Researcher Identifies Inflammatory Pathway That Offers VEGF-Independent Target for Diabetic Macular Edema Drugs
May 21, 2015 (Newswise) — Diabetic macular edema (DME) is a leading source of vision loss around the world, affecting about a fifth of people with long-term diabetes. Drugs that target a protein known as VEGF (vascular endothelial growth factor) inside the eye have greatly improved the treatment options in recent years, but only about half of DME patients are fully responsive to these new therapies.
Research in the lab of Edward P. Feener, Ph.D., Investigator in the Section on Vascu
May 20, 2015 (Physician's Briefing) — For older Medicare beneficiaries with type 2 diabetes mellitus (T2DM), early insulin initiation offers clinical benefit, according to a study published online May 8 in the Journal of the American Geriatrics Society.
Rituparna Bhattacharya, Ph.D., from West Virginia University in Morgantown, and colleagues examined the impact of the timing of insulin initiation in a cohort of older (=65 years) Medicare beneficiaries with T2DM. Participants were classified acc