Early Communication About Safety of Lantus (insulin glargine)
July 1, 2009 (FDA) - FDA is aware of four recently-published observational studies that looked at the use of Lantus (insulin glargine) and possible risk for cancer in patients with diabetes. Three of the four studies suggest an increased risk for cancer associated with use of Lantus. See http://www.diabetologia-journal.org/cancer.html.
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Young Black Women Prone to Gain More Unhealthy Abdominal
July 1, 2009 (Press Release) - Black women ages 20 to 29 are more prone to pack on unhealthy abdominal and visceral fat than Hispanic women the same age, and as compared to their elders, according to researchers from Wake Forest University Baptist Medical Center and colleagues.
The new research shows that accumulation of abdominal fat that increases risk of type 2 diabetes is greatest in young adulthood for blacks and Hispanics, said endocrinologist Kristen G. Hairston, M.D., M.P.H., lead author of an article published online June 1 by the American Diabetes Association. The study is the first to look at a large minority cohort using computed tomography (CT) scanning to measure longitudinal changes over time in visceral and subcutaneous adipose tissue, which are different types of abdominal fat.
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UT Researcher: Interferon Alpha Can Delay Full Onset of Type I Diabetes
July 1, 2009 (EurekAlert) - A low dose of oral interferon alpha shows promise in preserving beta cell function for patients with newly diagnosed type 1 diabetes, or juvenile diabetes, according to researchers at The University of Texas Medical School at Houston.
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Joint Replacement Patients with Diabetes Greatly Benefit From Controlled Glucose
July 1, 2009 (EurekAlert) - Diabetics undergoing total joint replacement often are at a higher risk of experiencing complications after surgery due to various pre-existing health conditions. According to a new study published in the July 2009 issue of The Journal of Bone and Joint Surgery (JBJS), those complications are less likely to occur when a diabetic patient has glucose levels under control.
"We found that controlled glucose levels really do make a difference for the patient," said study co-author Milford Marchant Jr., MD, an orthopaedic surgeon who conducted the study with colleagues of the Adult Reconstruction Section at Duke University Medical Center.
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U of Minnesota Finds Treatment That Significantly Slows Progression of Eye Damage in Persons with Type 1 Diabetes
July 1, 2009 (EurekAlert) - University of Minnesota Medical School researcher Michael Mauer, M.D., has found a treatment that significantly slows the progression of eye injury in people with type 1 diabetes, a common complication caused by this disease. By administering an antihypertensive, medication commonly prescribed to treat high blood pressure, Mauer and colleagues were able to slow progression of diabetic eye damage in more than 65 percent of participants involved in the study.
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Lap-Band Weight-Loss Surgery Can Reverse Metabolic Syndrome in Obese Teens
July 1, 2009 (EurekAlert) - A new study of obese adolescents has shown that laparoscopic gastric banding surgery -- the "Lap-Band" procedure -- not only helps them achieve significant weight loss but can also improve and even reverse metabolic syndrome, reducing their risk for cardiovascular disease and diabetes.
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ADA Releases Updated Position Paper on Vegetarian Diets
July 1, 2009 (EurekAlert) - The American Dietetic Association has released an updated position paper on vegetarian diets that concludes such diets, if well-planned, are healthful and nutritious for adults, infants, children and adolescents and can help prevent and treat chronic diseases including heart disease, cancer, obesity and diabetes.
ADA's position, published in the July issue of the Journal of the American Dietetic Association, represents the Association's official stance on vegetarian diets:
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AACE Response to Insulin Glargine Cancer Risk Articles in Diabetologia
June 29, 2009 (Press Release) - On June 26, 2009 several articles published online in Diabetologia by the European Association for the Study of Diabetes investigated the possible relationship between use of insulin glargine (Lantus, sanofi-aventis) and the development of certain malignancies. The authors themselves, and the accompanying editorial, cautioned against over-interpretation of their limited data and analyses, which precluded them from drawing any firm conclusions. For example, there were contradictory findings among the studies, patient populations were not always comparable, and the duration of observation was short. Nonetheless, since the relationship of type 2 diabetes to cancer is of critical importance, further study is warranted.
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Possible Link Between Insulin Glaragine and Cancer Prompts Urgent Call for More Research
June 30, 2009 (Diabetologia) - Worldwide, there are over 200 million people with diabetes. About 10% of these develop diabetes in early life, and most of them have what is known as type 1 diabetes. People with type 1 diabetes have an absolute reliance upon insulin treatment for their continued health and well-being. Type 2 diabetes, which affects the remaining 90%, typically develops later in life and may be associated with excess weight. People with type 2 diabetes are able to make some of their own insulin, which means that they can usually be treated with diet and tablets in its early stages. At a later stage, however, many patients with type 2 diabetes lose the ability to produce their own insulin, and will then need insulin injections to maintain their health.
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Statement From IDF on Studies Suggesting Possible Link Between Insulin Glargine and Cancer
June 29, 2009 (EurekAlert) - The International Diabetes Federation (IDF) today called for urgent assessment and responses from regulatory authorities into a possible link between the use of insulin glargine (an insulin analogue) and increased risk of cancer based on findings published on 26 June, 2009 in Diabetelogia, the journal of the European Association for the Study of Diabetes (EASD).
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Hypoglycemia During Hospitalization Linked to Higher Mortality Risk
June 29, 2009 (Brigham and Women's) - Researchers at Brigham and Women’s Hospital (BWH) found that diabetics hospitalized for non-critical illnesses who develop hypoglycemia during hospitalization have an increased likelihood of remaining hospitalized longer and a greater risk of mortality both during and after hospitalization. This research appears in the July 2009 issue of Diabetes Care.
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Novel Non-Surgical Therapy Dramatically Increases Weight Loss in Obese Patients; Results from Pilot Clinical Study Presented at ASMBS
June 26, 2009 (Press Release) - GI Dynamics, a leader in non-surgical treatments for type 2 diabetes and obesity, today announced results from a pilot clinical study which demonstrated the substantially enhanced weight loss effects of combining the company’s EndoBarrier Gastrointestinal Liner with a new EndoBarrier Flow Restrictor. The EndoBarrier Flow Restrictor provides an adjustable restriction at the outlet of the stomach and is designed to delay gastric emptying, an additional mechanism which adds to the therapeutic effects of the liner. The results were presented today at the 26th annual meeting of the American Society for Metabolic and Bariatric Surgery (ASMBS).
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Dietary Fat Linked to Pancreatic Cancer
Juner 26, 2009 (EurekAlert) - High intake of dietary fats from red meat and dairy products was associated with an increased risk of pancreatic cancer, according to a new study published online June 26 in the Journal of the National Cancer Institute.
This study was undertaken because research relating fat intake to pancreatic cancer was inconclusive.
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Trio of Signals Converge to Induce Liver and Pancreas Cell Development
June 26, 2009 (Newswise) - Understanding the molecular signals that guide early cells in the embryo to develop into different organs provides insight into ways that tissues regenerate and how stem cells can be used for new therapies. With regenerated cells, researchers hope to one day fill the acute shortage in pancreatic and liver tissue available for transplantation in cases of type I diabetes and acute liver failure.
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