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I don't have personal exp., but this is what is out on the web:
Prostate-specific antigen (PSA) is a substance produced by both normal and cancerous prostate cells. When prostate cancer grows or when other prostate diseases are present, the amount of PSA in the blood often increases.
A PSA test is generally said to be in the normal range when it is reported to be between 0 and 4 nanograms per milliliter, sometimes abbreviated as ng/mL on the lab report.
If the results are greater than 4 ng/mL, your physician may suggest a biopsy, which is the only test available to diagnose prostate cancer.
Guidelines published in 2005 by the National Comprehensive Cancer Network (NCCN) suggest that the threshold for consideration of a biopsy should be lower. The NCCN guidelines now recommend consideration of biopsies for men with PSA levels in the range of 2.5 to 4.0 ng/mL.1
It may also be useful to keep track of how your PSA level changes over a period of time. If your PSA level is rising your physician may suggest a biopsy.
PSA test results can be confusing and do not mean that cancer is present. Certain other conditions, such as benign prostatic hypertrophy (also called BPH - a type of noncancerous prostate enlargement) and prostatitis (inflammation of the prostate), may cause an abnormal PSA result.
good luck
Joe
_________________ Joe
joelicorcie at netscape dot net
Re:psa numbers? by tracy45 Sun Oct 07, 2007 2:55 pm
tracy45 Posts: 33 Joined: Wed Oct 03, 2007 8:50 am
A year ago I was diagnosed with prostate cancer and had a PSA of 2.7. After 42 radiation sessions, my PSA is now at 0.5 and dropping which means that the cancer was found early and treated. Normally, any PSA over 4.0 is suspect for possible cancer, but as my PSA was less than that with cancer, always rely on a good urologist for testing and diagnosis.
Re:psa numbers? by doug8164 Sun Dec 09, 2007 9:59 pm
doug8164 Posts: 7 Joined: Sun Dec 09, 2007 9:42 am
I had a bladder infection and was treated for same - with Bactrin. The Dr, did blood tests and found my PSA 10.0 He referred me to a Urologist after I warned him that the other dr would not be permitted to perform a DRE. The Urologist tested my urine, said nothing and insisted he perform a DRE, NO WAY.
Well when I visited my RA dr for fibromyalgia, I told her the story. She said I did not have Prostate cancer. <- I know what most will say "She is not a Urologist". -> TRUE. She treated my condition as prostatitis (prostate infection - secondary to the bladder infection). The infection cleared and I take Ultra Saw Palmetto Formula for prostate health. My primary care phy took blood recently and the PSA was .79. I think I made a good decision.
Elevated PSA does not necessarily mean cancer. I DO have my PSA taken often to monitor my prostate health. If PSA increases, I with my phy will monitor same for say six months - all along checking for prostatitis.
Go forward with more confidence. Trust, but verify!
_________________ "He is no fool, who gives what he cannot keep - to gain what he cannot lose."
Re: psa numbers? by gegan Mon Nov 02, 2009 6:07 pm
I just went through a whirlwind in my health. In July my doctor told me I had a PSA test over 4.0. She recommended I see a urologist for a exam and biopsy. The biopsy indicated I had a Gleason score of 3+3 = 6. After investigating and agonizing over all the options I just had brachytherapy done a couple weeks ago. I'm doing well for the most part. As the one commerical on TV indicates where the men have a going and going problem, I am a frequent user of the restroom. Hopefully this tapers off in the future.
I am a strong advocate of men getting checked out frequesntly. The PSA is a simple blood test. Some doctors say the developers of the test push it to make money. I say if it can show a problem early so what.
They say they caught my cancer early. I get to live with not really knowing for a while. Hopefully my PSA drops to zero in three months, but I have questions as to what this will do to my life as I now know it. Have my fingers crossed.
Re: psa numbers? by pauliewog Mon Nov 02, 2009 11:33 pm
pauliewog Posts: 69 Joined: Tue Dec 02, 2008 12:21 am
11 year survivor of prostate cancer. PSA was 39 @ Dx. 1st I had ever had done,(and then only because I requested it).Biopsy revealed 70% of samples cancerous. As with last poster I too had Bracytherapy and EXT beam radiation. Good results.
While I did not have the opportunity to track a rise in PSA. I learned a lot about it while researching treatment options. A number over 4 is usually considered a cause for concern. If only slightly over, most docs will suggest tracking PSA over time to see what if any the rate of increase is. A sudden rise,(few months), will normally trigger a biopsy.
My PSA numbers after treatment went down to 1.65, and then gradually lowered to less than one. Last test was 0.11. I don't think a reading of zero is ever realized. But that does not mean there is cancer present. As others have pointed out there are other causes that may play into the PSA number. If you are going to have a PSA test and DRE,(digital rectal exam), be sure that the DRE is done AFTER blood is drawn for PSA as manipulation of the prostate can cause a slight rise in the PSA number,(as can having sex the night before).
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