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February 9th, 2012
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I wasn't at all pleased with how switching to a 1:30pm Lantus injection was working for me. It was just too stressful to make sure I took it exactly then and too bothersome to compete with a post-breakfast high and a lack-of-Lantus high. So I switched.

 

I split the dose for 1:30pm and roughly 11:30pm (I say roughly because the last two days I've been scrambling around the mall or at Christmas tree lots getting my mom's house ready for Friday's party). I started with a 20 unit and a 15 unit split (originally was on 36 units). I haven't had a chance to sit down with the logbook (see said scrambling), but I have felt some differences.

 

First of all is my morning numbers. Those morning lows are back. This morning, a nice and early 55 woke me up...along with my mother on the phone and the cat in my ear. And this is after a 64 yesterday morning which made me lower the 15 units to 12 units.

 

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Tuesday night, I switched my Lantus over to a once-per-day shot instead of the split doses I'd been using previously. I started with 22 units of Lantus at 8pm. I knew I'd see some highs, but I didn't want to risk an unexpected night low after making the first switch.

 

And I did see some elevation. I ran mostly in the 180-290 range all through Wednesday, which wasn't as high as I was expecting really. I made sure to consider food in the highs, along with the usual post-breakfast spike. And I was confident that a few more units of Lantus might do the trick (or at least get me closer).

 

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I've been on Lantus for about ten years now. I tried different insulins over the years (NPH, Ultralente, and the like) plus that almost two year stint on the pump. Lantus seems the best for me, although I'd still like to try Levemir. Lantus keeps me stable without giving me constant lows.

 

The drops are predictable. With split doses, I get fairly steady blood sugars. Overall, I've been happy with Lantus for years. But lately, I've noticed a change that I've very rarely experience but often heard about.

 

With every injection lately, I'm experiencing a lot of pain. It isn't happening with Humalog, just my Lantus. I'm not sure if it's the location or just the insulin. I generally give my morning and evening Lantus injections in my bottom. Both my doses are too big for what's comfortable for me elsewhere.

 

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The problem that I have with Lantus is that one dose just doesn't cut it for me. It claims a 24 hour lifespan, but honestly...it's probably more like 20 hours on a good day. Which means that my blood sugars start spiking towards the end of that injection.

 

That's exactly why I split my doses however many years ago. It worked, dropping my A1c like a lead balloon. And now that my schedule nearly forced me into either the insane asylum or a once-per-day dose, I'm struggling to find an appropriate time for my Lantus injection.

 

An evening shot wasn't working because I was having to take such a bulk of insulin that I was dropping way below my safety point by morning. And now I've switched to an early afternoon injection, but I'm afraid that looks like it's bombing as well.

 

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As I looked at my averages last night in preparation for my Friday endo check-up, I couldn't help but complain to myself that there is no pattern. Every day is different, often drastically so. I can't find any constant area. There aren't variables causing these random shifts, at least not to the naked eye.

 

First, there's my morning blood sugars. Sometimes I wake up low even after a bedtime snack with no bolus. And sometimes I wake up in the 200 or 300 range with no apparent cause. Because of my history of seizures and severe lows, I lean towards the lows though. At this point in my life, I'd rather wake up 300 occasionally instead of trying to raise my insulin to counteract those highs.

 

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Low blood sugars that happen in the middle of the night really suck! You're dead asleep, and then all of the sudden your dreams start getting confusing and weird. You start feeling like you should probably drag yourself out of bed and get something from your sugar stash. You barely have the energy to get up and then once you do you stumble around and nearly black out. You feel confused and you act and look as though you've had WAY too much to drink. Then after you climb back into bed you just sit there for a while and you try to wait patiently while your sugar goes back up or until you feel good enough to fall back asleep.

Well, that's what happened to me last night, and what I tend to experience almost once a week.
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Right now, I'm staring at my logbook trying to decide what changes I need to make and what else I want to try with all this. This past week has been a bit rocky so my averages are all over the place. Mostly, they're high. At least higher than I want them to be. So while I'm staring at my book, I'm trying to piece together this last week and figure out what is going on with these numbers.

 

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Because of my recent tummy troubles, I've decided to put off the Metformin start for at least another week. So instead of starting Metformin today, I've decided to get back into the groove of the need for insulin. Instead of purposefully skipping Lantus doses and fudging my boluses, I'm going to get into the routine of doing these things right.

 

My current Lantus doses are split at midnight (16 units) and noon (18 units). However, I've had a lot of trouble remembering them or getting them on time lately without a schedule. So I think I need to try a one dose Lantus shot for awhile. I've done it before and it just doesn't give me as tight of control as I like, but it's better than no insulin at all.

 

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In the past three nights, I've seen the same diabetes pattern. At 10:30pm, I suddenly drop. All three times have been a little over an hour after a meal and roughly seven hours after my afternoon Lantus injection. I stay low for a few hours and after several treatments, I pop up to the 140 range (or the 200s like last night).

 

I'm extremely frustrated by this. The lows are definitely taking their toll on my body, as usual. My weight is up a few pounds. And I'm generally just feeling weak and out of sorts. Not the fatigue of the weeks of highs, but a general low energy that results in me eating just to feel a little better. And lots of cravings for sugar mixed in there.

 

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"Take two tablets every four to six hours, up to four times daily."

 

These are the standard dosing instructions we see on drugstore bottles of aspirin, acetominophen, and ibuprofen. "Take two [at the time]" is such a common instruction for medications that it's almost become a cultural joke. But if you go over to the drug manufacturer's site, or to a site like drugs.com, you'll find another story that may cause you to question the first. That story is the drug's activity curve.

 

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Lindsey Guerin
Lindsey GuerinLindsey is a typical, yet unique, Texas girl who loves shopping, movies and reading. She loves to travel and take risks. She dreams of diabetes cures, never-ending cheesecake and her own airplane. The rest you can discover in her blog! (Read More)
Nicole Purcell
Nicole PurcellNicole Purcell lists having type 1 diabetes last when she's asked to provide information about herself - because that's where it belongs.

(Read More)
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