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February 10th, 2012
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I received the normal JDRF research newsletter the other day. As usual, I perused the updates on diabetes. There was a large article on the new stem cell legislation movement, but I quickly passed over it. But two articles did catch my eye.

 

One was regarding "Insulin Fragment" Therapy, which I hadn't heard about before this newsletter. A study from the UK showed that "proinsulin peptide" therapy could seemingly restore the immune system without any adverse side effects (like the immunotherapy treatments for pancreas and cell transplants). More research had to be done, but it was still an important milestone.

 

The other article had to do with protein regeneration for adult beta cells. It was a snippet of an article regarding the prospect of regeneration and replication of beta cells for type 1s. All it did was leave hope. Hope for regrowth. Hope for a life without diabetes.

 

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By now I am sure most of you have heard about the “breakthrough” discovery made regarding a possible cure for type 1.


When I saw the report on NBC nightly news I was floored. I sat in my chair staring in front of the TV. My son said, “that is cool huh dad?”


I just looked at him and said, “I guess it is.”


His weird look was probably a mirror of the weird look I felt I had on my face. How was I supposed to feel about this?

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"So, Charlie, did you hear? Scientists are working on a possible cure for diabetes that could come from testicles?"

 

 

"Huh? The what?"

 

 

 

"You don’t know what your testicles are?"

 

 

 

"Uh uh."

 

 

 

"You know. It’s your, uh …

 

 

 

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I was diagnosed with type 1 diabetes twenty-five years ago. Twenty-five years is a long time to live with something. It is an especially long time to live with something that requires tight control. Twenty-five years is enough time to have seen lots of bad days, lots of good days, and lots and lots of in betweens. And it is enough time for me to have had the good fortune of seeing vast improvements in access to information and treatment, developments and improvements in technology and even some improvements in (GASP!) what health insurers are willing to cover. (READ MORE)


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What if this was it? What if this was THE announcement? Where were you when you first heard the news?

 

We were in the living room. Susanne was sitting on the brown "site-change chair" with Charlie laying across her knees. She peeled the site off of Charlie's bottom while he resisted, elbowing her in the ribs and screaming, "break! break! break!"

 

Susanne begged him to be still.

 

And then suddenly everything stopped as we all became transfixed to the words coming out of Brian Williams' mouth on the television and the graphic over his left shoulder that said "Diabetes & Kids."

 

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This is World Diabetes Day, the first annual, and the international community is embracing its message by flying high the striking blue symbol of the disease. The message is about waking up the world to the growing impact of diabetes on our young and old- this year's theme focusing on children and adolescents. The innocent faces of the disease give a hammering reminder of what we are striving for, worldwide awareness, more scientific breakthroughs, and a much needed cure. (READ MORE)


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Yesterday, I discussed how I'd like diabetes healthcare providers and the healthcare industry to better use existing tests and technologies, and how I believe our current crop of devices and programs might be developed in the near-term future. Today I'm going to discuss items that will take a bit longer to develop and get through FDA approval, or which may take technological and medical breakthroughs to bring to fruition.

 

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One of the odd observances of the Christmas Skeptic is the effect of today's gift-giving Santa Claus on the development of greed amongst children. The observation is somewhat paradoxical considering greed is considered one of the Seven Deadly Sins.

 

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CP: I'm here with lumberjack, one-time monopoly champion, brother-in-law extraordinaire and a downright handsome speciman of a man, Patrick Mauceri. Thanks for joining us today.
 

PM: Hey C-dog.  No problem. Thanks for having me.  Monopoly champ?


CP: Ignore me.
 

CP: Interesting place you chose to meet me at today. So I just put my coins in here and the little peephole opens up? Do people with diabetes frequent this sort of place often?


PM: Well it's our little speakeasy. Only instead of bootlegged whiskey, they serve expensive juice boxes and orange slices. Can I buy you a drink?

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Much buzz has been going around the diabetes community about the recent announcement of the JDRF/Animas partnership to develop a "first generation artificial pancreas", and rightly so. The ability to eat like a "normal person", to not have to worry about debilitating highs and lows, to be able to sleep without fear of not waking up again... these are things which are, quoth Hamlet, "devoutly to be wish'd". That the road between here and there is not so simple a passage as we might hope, is well-known, and much littered with papers sporting words like "cure", "encapsulation", "transplant", "gene therapy", and -- of course -- "artificial pancreas". (READ MORE)


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Julia
JuliaJulia lives behind the Tofu Curtain, in the Pioneer Valley, in Western Massachusetts. It's a nice place. She likes it there. Her eldest daughter, Olivia, has type 1 diabetes. She's also 13. It's a real toss-up as to which is more difficult -- the diabetes or the teen-age drama. (Read More)
Michelle Kowalski
Michelle KowalskiMichelle Kowalski, a writer, editor and photography hobbiest living in Phoenix, was diagnosed with Type 2 diabetes in February 2005. In January 2008, as part of her quest to start on an insulin pump, Michelle learned that she actually has type 1 diabetes. (Read More)
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