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Each insulin has its own unique therapeutic effect. The onset of action of a particular insulin is how long it takes the hormone to start working at lowering blood glucose levels. The insulin peak is the point at which the dose is at the height of its therapeutic effectiveness, and the duration is how long the blood glucose lowering effect of a given insulin lasts from injection to end. Following is a list of insulin types available in the United States, along with their onset, peak, and duration. Talk to your healthcare provider about your insulin regimen.

*Novolin N is also sold as ReliOn at Wal-Mart in the U.S.

Onset: how much time it takes for the insulin to start affecting blood glucose levels
Peak: how long it takes for the insulin to reach maximum effectiveness
Duration: how long the insulin remains active upon blood glucose levels

Sources: Food & Drug Administration, NovoNordisk A/S, Sanofi-Aventis US, Eli Lilly and Company

These are approximate values for insulin effectiveness. Results may vary based upon the individual’s diet, exercise program, and the absorption of the injection site. Please consult your medical team when making any changes to your diabetes management.

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Reviewed by Francine Kaufman, MD. 4/08