Cholesterol Medications

There are several drug therapies that can help you lower your cholesterol and/or triglyceride levels.

Statins are the most common front-line treatment for anyone with an LDL of 100 mg/dl (5.56 mmol/L) or higher. They reduce LDL cholesterol by blocking a key step in the process of manufacturing cholesterol in the liver.

If statins are not producing the necessary results, bile-acid binding resins may be utilized.

Medication to lower their triglycerides is sometimes prescribed. There are several drug choices to lower triglycerides, namely fibric acid derivatives and nicotinic acid.

See the chart below for an overview of cholesterol drugs.

Your doctor can tell you what treatment is right for you. Always consult your medical team before making any changes to your diabetes management.

 


Types of Medication

Generic Names

Brand Names

What it Does

Statins

Atorvastatin

Lipitor 

  • Raises HDL,
  • Lowers LDL,
  • Lowers Triglycerides
  • Lowers Total Cholesterol

Fluvastatin

Lescol  

Lovastatin

Mevacor   Altocor  

Pitavastatin

Livalo 

Pravastatin

Pravachol 

Rosuvastatin

Crestor 

Simvastatin

Zocor 

Bile-Acid Binding Resins*

Cholestyramine

Prevalite  Questran Light 

  • Raises HDL,
  • Lowers LDL,
  • Lowers Triglycerides

Colesevelam

Welchol 

Colestipol

Colestid 

Fibric Acid Derivatives

Fenofibrate

TriCor 

Antara 

Triglide

Fenoglide 

Lipofen 

TriLipix 

  • Raises HDL,
  • Lowers Triglycerides

Gemfibrozil

Lopid 

Intestinal Cholesterol Absorption Inhibitor

Ezetimibe

Zetia  

  • Raises HDL,
  • Lowers LDL,
  • Lowers Total Cholesterol,
  • Lowers Triglycerides

Nicotinic Acid

Niacin

Niacor 
Niaspan 

 

  • Lowers LDL,
  • Lowers Triglycerides

Combination Medications

Ezetimibe
Simvastin

Vytorin  

  • Raises HDL,
  • Lowers LDL,
  • Lowers Total Cholesterol,
  • Lowers Triglycerides
Niacin
Lovastatin

Advicor 

  • Raises HDL,
  • Lowers LDL,
  • Lowers Triglycerides

Simvastin
Niacin

Simcor  

  • Raises HDL,
  • Lowers LDL,
  • Lowers Triglycerides
Amlodipine besylate
atorvastatin calcium

Caduet 

  • Lowers LDL
Sitagliptin
Simvastatin
Juvisync  
  • Raises HDL,
  • Lowers LDL,
  • Lowers Total Cholesterol,
  • Lowers Triglycerides
Prescription Supplements Omega-3-acid
-Ethyl esters
Lovaza 
  • Lowers extremely high Triglycerides
Icosapent ethyl Vascepa
  • An omega-3 fatty acid that lowers extremely high Triglycerides
Microsomal Triglyceride Transfer Protein Inhibitor Lomitapide JuxtapidTM
  • Lowers LDL cholesterol and total cholesterol in patients with homozygous familial hypercholesterolemia

 

*Side effects may include upset stomach and constipation, and may not be appropriate for people with diabetes gastroparesis.

SOURCE:
Grundy SM, Cleeman JI, Bairey Merz CN, Brewer HB, Clark LT, Hunninghake DB, Pasternak RC, Smith SC, Stone NJ; for the Coordinating Committee of the National Cholesterol Education Program. "Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines." Circulation. 2004; 110:227-239.

Reviewed by James A. Bennett 5/13.

Page: 1 | 2

Last Modified Date: February 25, 2014

All content on dLife.com is created and reviewed in compliance with our editorial policy.
Sources
  1. American Heart Association. Drug Therapy for Cholesterol. http://www.heart.org/HEARTORG/Conditions/Cholesterol/PreventionTreatmentofHighCholesterol/Drug-Therapy-for-Cholesterol_UCM_305632_Article.jsp. (Accessed 6/26/11).
  2. FDA. High Cholesterol — Medicines to Help You. http://www.fda.gov/ForConsumers/ByAudience/ForWomen/ucm118595.htm. (Accessed 6/26/11).
  3. Pharmacist's Letter. http://pharmacistsletter.therapeuticresearch.com/home.aspx?cs=&s=PL&AspxAutoDetectCookieSupport=1 (Accessed 5/13)
  4. U.S. Food and Drug Administration. FDA Approves Combination Therapy Juvisync. http://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/ucm274748.htm. (Accessed 10/7/11.)

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