What is LADA? (continued)
The Mystery Continues
Researchers still don't know whether autoimmune diabetes in adults is due to the same underlying disease process as type 1 diabetes in children, and there are many LADA questions that still need answers. In attempt to standardize the definition of LADA, the Immunology of Diabetes Society has recently proposed the following criteria: patients should be at least 30 years of age, positive for at least one of four antibodies commonly present in type 1 diabetic patients, and not treated with insulin within the first six month of diagnosis. (1)
No one can predict exactly how long a LADA patient will continue to produce insulin. For me, the slow process of beta-cell destruction has probably been ongoing for close to a decade. The crucial task for the physician is not to miss a LADA diagnosis. And once LADA is diagnosed, the physician should recognize that some LADA patients require insulin, and will respond best to a basal-bolus (or pump) approach. "Although given that LADA patients may have features of type 2 as well," says Dr. Bloomgarden, "they may benefit from concurrent treatment with various oral medicines."
Regardless of your age, if you are labeled as having type 2 diabetes but have no family history of diabetes and are not overweight, you may have in fact have LADA. Your doctor can check for this with a blood test for autoantibodies and c-peptide levels, which indicate the amount of insulin you are producing (a low c-peptide level suggests LADA). When deciding how to treat LADA, says Dr. Bloomgarden, ultimately, it's not the measurement of insulin, c-peptide, or antibodies that matters but rather the physician and patient both understanding when insulin is warranted. If it is, it's not a reason to panic. The sooner you are receiving the correct treatment, the better you should feel.
 Journal of Clinical Endocrinology and Metabolism December 2009, 94. jcem.endojournals.org
Reviewed by Joy Pape, RN, BSN, CDE, WOCN, CFNC. 2/13
Luscious Lemon Ice Cream Tropical Berry Squares with Rum Vegetable-Cheddar Frittata Scallops in Shiitakes Chocolate Raspberry Brownies Beef Round Steak With Herbs Turkey Roulade Chive Whole Wheat Drop Biscuits Herbed Angel Hair Pasta and Spinach Cheddar Pecan Biscuits
Let me count the ways. Actually I can’t count the ways; there are too many. But let me begin with nasty carbohydrates and how they torture me. I’m considering making “How Do I Hate Thee?” a series of blog posts, exploring the many different things I despise about diabetes. There is so much to hate about diabetes, but this one I place high on my list. Last Wednesday, a friend offered me and...